What is alpha-1 antitrypsin deficiency (AATD)?
Alpha-1 antitrypsin deficiency (AATD) is a genetic disease that causes a lack of the protein, alpha-1 antrypsin (A1AT) due to the inability to release and accumulate antiprotease from the liver. The symptoms of AATD include emphysema, cryptogenic cirrhosis, portal hypertension and other liver conditions. The current AATD treatment market reaches over USD 1 billion, and it is expected to grow up to USD 1.8 billion.